Switch of rhodopsin expression in terminally differentiated Drosophila sensory neurons

Simon G. Sprecher and Claude Desplan ()
Additional contact information
Simon G. Sprecher: Center for Developmental Genetics, New York University, 1090 Silver Center, 100 Washington Square East, New York, New York 10003-6688, USA
Claude Desplan: Center for Developmental Genetics, New York University, 1090 Silver Center, 100 Washington Square East, New York, New York 10003-6688, USA

Nature, 2008, vol. 454, issue 7203, 533-537

Abstract: Differentiated sensory neurons that switch fate Sensory neurons, once they have completed their embryonic development, usually maintain robust expression of specific sensory receptor genes, for example light colour-sensitive pigments. In this study, Simon Sprecher and Claude Desplan show that blue-sensitive (Rh5) neurons in the fruitfly's larval eye switch fate — and switch pigment — during metamorphosis to become green sensitive (Rh6) and form the adult eyelets, small organs on the top of the fly's head, which reset its circadian clock. The work opens the way to the genetic investigation of gene regulatory mechanisms controlling such rare fate-switching events in post-mitotic neurons.

Date: 2008
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature07062 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:454:y:2008:i:7203:d:10.1038_nature07062

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature07062

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().