Molecular architecture of native HIV-1 gp120 trimers

Jun Liu, Alberto Bartesaghi, Mario J. Borgnia, Guillermo Sapiro and Sriram Subramaniam ()
Additional contact information
Jun Liu: Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Alberto Bartesaghi: Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Mario J. Borgnia: Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Guillermo Sapiro: University of Minnesota, Minneapolis, Minnesota 55455, USA
Sriram Subramaniam: Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA

Nature, 2008, vol. 455, issue 7209, 109-113

Abstract: HIV/AIDS: gp120 structure changes This paper investigates the structure of the HIV the gp120 coat protein of HIV by cryo-electron tomography and molecular modelling. Comparison of gp120 structures in an unbound state, bound to a neutralizing antibody and bound to CD4 cell surface protein provides insight into the conformational changes that occur during antibody neutralization and attachment to target cells.

Date: 2008
References: Add references at CitEc
Citations: View citations in EconPapers (5)

Downloads: (external link)
https://www.nature.com/articles/nature07159 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:455:y:2008:i:7209:d:10.1038_nature07159

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature07159

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().