Stabbed in the BAX

Douglas R. Green and Jerry E. Chipuk
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Douglas R. Green: St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA. douglas.green@stjude.org
Jerry E. Chipuk: St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA. douglas.green@stjude.org

Nature, 2008, vol. 455, issue 7216, 1047-1049

Abstract: Apoptotic cell death is an intricate and highly regulated process. To initiate apoptosis, the protein BIM binds to a hitherto unrecognized site on the BAX protein to trigger permeabilization of the outer mitochondrial membrane.

Date: 2008
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DOI: 10.1038/4551047a

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