Enzyme knocked for a loop

Ronald L. Mellgren
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Ronald L. Mellgren: University of Toledo College of Medicine, Toledo, Ohio 43614-2598, USA. ronald.mellgren@utoledo.edu

Nature, 2008, vol. 456, issue 7220, 337-338

Abstract: Protein-digesting enzymes are kept on a tight leash to stop them from wantonly attacking targets. Two crystal structures show how an inhibitory protein domain gags one such enzyme without being chewed up itself.

Date: 2008
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DOI: 10.1038/456337a

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