The Beagle in a bottle

Angus Buckling, R. Craig Maclean, Michael A. Brockhurst and Nick Colegrave
Additional contact information
Angus Buckling: University of Oxford
R. Craig Maclean: University of Oxford
Michael A. Brockhurst: School of Biological Sciences, University of Liverpool
Nick Colegrave: School of Biological Sciences, University of Edinburgh

Nature, 2009, vol. 457, issue 7231, 824-829

Abstract: Abstract Why infer evolution when you can watch it happen in real time? This is the basic premise of using populations of fast-replicating microorganisms in test tubes to study evolution. The approach, known as experimental evolution, has provided a way of testing many of the key hypotheses that arose from the modern evolutionary synthesis. However, details of the unnatural histories of microorganisms in test tubes can be extrapolated only so far. Potential future directions for the approach include studying microbial evolution for its own sake under the most natural conditions possible in the test tube, and testing some qualitative theories of genome evolution.

Date: 2009
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DOI: 10.1038/nature07892

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