A Notch above other inhibitors

Paramjit S. Arora and Aseem Z. Ansari
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Paramjit S. Arora: New York University, New York 10003, USA. arora@nyu.edu;
Aseem Z. Ansari: University of Wisconsin–Madison, Madison, Wisconsin 53706, USA. ansari@biochem.wisc.edu

Nature, 2009, vol. 462, issue 7270, 171-173

Abstract: A tenet of drug discovery states that molecules greater than a certain size don't enter cells. But not only do certain synthetic peptides refute this idea, they also inhibit 'undruggable' biological targets.

Date: 2009
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DOI: 10.1038/462171a

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