Exceptional structured noncoding RNAs revealed by bacterial metagenome analysis

Zasha Weinberg, Jonathan Perreault, Michelle M. Meyer and Ronald R. Breaker ()
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Zasha Weinberg: Howard Hughes Medical Institute,
Jonathan Perreault: Cellular and Developmental Biology
Michelle M. Meyer: Cellular and Developmental Biology
Ronald R. Breaker: Howard Hughes Medical Institute,

Nature, 2009, vol. 462, issue 7273, 656-659

Abstract: Remarkable environmental RNAs Computational analysis of environmental DNA and RNA sequences from material extracted from seawater samples has revealed the presence of abundant bacterial noncoding RNAs that resemble large ribozymes in size and complexity. Of particular interest are two new-found RNAs, called GOLLD and HEARO, that are amongst the largest and most complex RNAs discovered to date. These findings suggest that there are many more RNAs with extraordinary size, structural complexity, or other exceptional characteristics, waiting to be discovered in waters, soils and other environments yet to be explored.

Date: 2009
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DOI: 10.1038/nature08586

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