Des Marais & Rausher reply

David L. Des Marais () and Mark D. Rausher ()
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David L. Des Marais: Box 90338, Duke University
Mark D. Rausher: Box 90338, Duke University

Nature, 2009, vol. 462, issue 7274, E2-E3

Abstract: Abstract Replying to: T. Barkman & J. Zhang Nature 462, 10.1038/nature08663 (2009) Barkman and Zhang 1 level two criticisms at our report of escape from adaptive conflict (EAC)2. The first criticism is that our evidence of repeated adaptive substitution in the DFR-A/C lineage is consistent with either EAC or neofunctionalization in that lineage. As indicated in our original report2, we do not disagree with this claim, but believe it misses the point that the hallmark of EAC is the adaptive improvement of function in both duplicate lineages. The repeated positive selection in the DFR-A/C lineage simply demonstrates improvement of some as yet unspecified function in that lineage.

Date: 2009
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DOI: 10.1038/nature08664

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