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A brake on lipid synthesis

Fikadu G. Tafesse and Joost C. M. Holthuis
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Fikadu G. Tafesse: Fikadu G. Tafesse and Joost C. M. Holthuis are in the Bijvoet Center and the Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, the Netherlands. j.c.holthuis@uu.nl
Joost C. M. Holthuis: Fikadu G. Tafesse and Joost C. M. Holthuis are in the Bijvoet Center and the Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, the Netherlands. j.c.holthuis@uu.nl

Nature, 2010, vol. 463, issue 7284, 1028-1029

Abstract: Although sphingolipids are vital cellular components, the path to their production is paved with toxic intermediates. Orm proteins allow cells to form these lipids without killing themselves in the process.

Date: 2010
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DOI: 10.1038/4631028a

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