Targeting early infection to prevent HIV-1 mucosal transmission

Ashley T. Haase ()
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Ashley T. Haase: University of Minnesota

Nature, 2010, vol. 464, issue 7286, 217-223

Abstract: HIV: transmission failure The goal of preventing sexual mucosal transmission of HIV/AIDS, the principal route of acquisition, remains a priority if the pandemic is to be contained and HIV ultimately eradicated. In a review focused on pathogenesis in tissues relevant to mucosal transmission, particularly in the well characterized simian immunodeficiency virus rhesus macaque model, Ashley Haase argues that prevention strategies should target the earliest stage of infection — using both vaccines and microbicides.

Date: 2010
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DOI: 10.1038/nature08757

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