Modulation of Shigella virulence in response to available oxygen in vivo

Benoit Marteyn, Nicholas P. West, Douglas F. Browning, Jeffery A. Cole, Jonathan G. Shaw, Fredrik Palm, Joelle Mounier, Marie-Christine Prévost, Philippe Sansonetti () and Christoph M. Tang ()
Additional contact information
Benoit Marteyn: Centre for Molecular Microbiology and Infection, Flowers Building, Imperial College London
Nicholas P. West: Centre for Molecular Microbiology and Infection, Flowers Building, Imperial College London
Douglas F. Browning: School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Jeffery A. Cole: School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Jonathan G. Shaw: University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK
Fredrik Palm: Biomedical Center, Uppsala University
Joelle Mounier: Unité de Pathogénie Microbienne Moléculaire, and Unité INSERM786, Institut Pasteur, 28 rue du Dr Roux, F-75724 Paris Cédex 15, France
Marie-Christine Prévost: Plateforme de Microscopie électronique, Institut Pasteur, 25 Rue du Docteur Roux, F-75724 Paris cedex 15, France
Philippe Sansonetti: Unité de Pathogénie Microbienne Moléculaire, and Unité INSERM786, Institut Pasteur, 28 rue du Dr Roux, F-75724 Paris Cédex 15, France
Christoph M. Tang: Centre for Molecular Microbiology and Infection, Flowers Building, Imperial College London

Nature, 2010, vol. 465, issue 7296, 355-358

Abstract: Oxygen and Shigella flexneri virulence Shigella flexneri, a bacterial dysentery pathogen, employs a type III secretion system to inject virulence factors into host cells during enteric infection. It is now suggested that oxygen availability during different phases of infection tightly regulates expression of the secretion system as well as the secretion of virulence factors.

Date: 2010
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature08970 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:465:y:2010:i:7296:d:10.1038_nature08970

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature08970

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().