How to accurately bypass damage

Suse Broyde and Dinshaw J. Patel
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Suse Broyde: New York University, New York, New York 10003, USA. broyde@nyu.edu
Dinshaw J. Patel: Dinshaw J. Patel is in the Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA. pateld@mskcc.org

Nature, 2010, vol. 465, issue 7301, 1023-1024

Abstract: Ultraviolet radiation can cause cancer through DNA damage — specifically, by linking adjacent thymine bases. Crystal structures show how the enzyme DNA polymerase η accurately bypasses such lesions, offering protection.

Date: 2010
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DOI: 10.1038/4651023a

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