Emerging properties of animal gene regulatory networks

Eric H. Davidson ()
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Eric H. Davidson: California Institute of Technology

Nature, 2010, vol. 468, issue 7326, 911-920

Abstract: Gene networking in the embryo As the various cell types in an adult organism all share one genome, the differences between them are determined by which genes are turned on or off by their specific repertoires of regulatory proteins. The coordinated expression of these regulators itself follows from the successive gene regulatory networks (GRNs) put in place during embryonic development. In a Review in this issue of Nature, Eric Davidson outlines the emerging principles that distinguish the GRNs that control the expression of terminal markers from those that control the interactions among embryonic regulators themselves.

Date: 2010
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DOI: 10.1038/nature09645

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