When catastrophe strikes a cell
Jose M. C. Tubio and
Xavier Estivill ()
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Jose M. C. Tubio: Jose M. C. Tubio and Xavier Estivill are in the Genes and Disease Programme, Center for Genomic Regulation (CRG) and Pompeu Fabra University, Barcelona, Catalonia 08003, Spain.
Xavier Estivill: Jose M. C. Tubio and Xavier Estivill are in the Genes and Disease Programme, Center for Genomic Regulation (CRG) and Pompeu Fabra University, Barcelona, Catalonia 08003, Spain.
Nature, 2011, vol. 470, issue 7335, 476-477
Abstract:
In 2–3% of cancers, a single genetic event may have led to hundreds of genomic rearrangements confined to just one or a few chromosomes. This finding challenges the conventional view of how mutations accumulate in oncogenesis.
Date: 2011
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DOI: 10.1038/470476a
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