Long-term evolution and transmission dynamics of swine influenza A virus

Dhanasekaran Vijaykrishna, Gavin J. D. Smith, Oliver G. Pybus, Huachen Zhu, Samir Bhatt, Leo L. M. Poon, Steven Riley, Justin Bahl, Siu K. Ma, Chung L. Cheung, Ranawaka A. P. M. Perera, Honglin Chen, Kennedy F. Shortridge, Richard J. Webby, Robert G. Webster, Yi Guan () and J. S. Malik Peiris ()
Additional contact information
Dhanasekaran Vijaykrishna: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Gavin J. D. Smith: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Oliver G. Pybus: University of Oxford
Huachen Zhu: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Samir Bhatt: University of Oxford
Leo L. M. Poon: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Steven Riley: Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China
Justin Bahl: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Siu K. Ma: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Chung L. Cheung: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Ranawaka A. P. M. Perera: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Honglin Chen: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Kennedy F. Shortridge: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Richard J. Webby: St Jude Children’s Research Hospital
Robert G. Webster: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
Yi Guan: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
J. S. Malik Peiris: Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China

Nature, 2011, vol. 473, issue 7348, 519-522

Abstract: Swine flu surveillance in pigs Pigs are recognized as important 'mixing vessels' in which influenza viruses can undergo reassortment, but despite the resulting threat to human health there has been a general lack of adequate virus surveillance in pig populations. Malik Peiris and colleagues present a large data set of hundreds of swine influenza isolates and swine sera collected over 12 years of systematic surveillance in southern China, supplemented with samples stretching back 34 years. The data set provides a detailed picture of the evolutionary dynamics of swine influenza in this region.

Date: 2011
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DOI: 10.1038/nature10004

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