Inference of human population history from individual whole-genome sequences
Heng Li () and
Richard Durbin ()
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Heng Li: The Wellcome Trust Sanger Institute
Richard Durbin: The Wellcome Trust Sanger Institute
Nature, 2011, vol. 475, issue 7357, 493-496
Abstract:
Human population in the genes The history of human population size is important to understanding human evolution. Heng Li and Richard Durbin use complete genome sequences from Chinese, Korean, European and Yoruban (West African) individuals to estimate population sizes between 10,000 and 1 million years ago. They infer that European and Chinese populations had very similar size histories until about 10,000–20,000 years ago. The European, Chinese and African populations all had an elevated effective population between 60,000 and 250,000 years ago. Genomic analysis suggests that the differentiation of genetically modern humans may have started as early as 100,000–120,000 years ago.
Date: 2011
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DOI: 10.1038/nature10231
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