Predicting mutation outcome from early stochastic variation in genetic interaction partners

Alejandro Burga, M. Olivia Casanueva and Ben Lehner ()
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Alejandro Burga: EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation (CRG) and Universitat Pompeu Fabra (UPF)
M. Olivia Casanueva: EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation (CRG) and Universitat Pompeu Fabra (UPF)
Ben Lehner: EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation (CRG) and Universitat Pompeu Fabra (UPF)

Nature, 2011, vol. 480, issue 7376, 250-253

Abstract: Mutations sometimes only affect a subset of genetically identical individuals; here, variation in the expression of chaperones and gene duplicates is shown to predict mutation outcome in C. elegans.

Date: 2011
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DOI: 10.1038/nature10665

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