Adherens junction protein nectin-4 is the epithelial receptor for measles virus

Michael D. Mühlebach, Mathieu Mateo, Patrick L. Sinn, Steffen Prüfer, Katharina M. Uhlig, Vincent H. J. Leonard, Chanakha K. Navaratnarajah, Marie Frenzke, Xiao X. Wong, Bevan Sawatsky, Shyam Ramachandran, Paul B. McCray, Klaus Cichutek, Veronika von Messling, Marc Lopez and Roberto Cattaneo ()
Additional contact information
Michael D. Mühlebach: Paul-Ehrlich-Institut, 63225 Langen, Germany
Mathieu Mateo: Mayo Clinic
Patrick L. Sinn: Department of Pediatrics University of Iowa Carver College of Medicine
Steffen Prüfer: Paul-Ehrlich-Institut, 63225 Langen, Germany
Katharina M. Uhlig: Paul-Ehrlich-Institut, 63225 Langen, Germany
Vincent H. J. Leonard: Mayo Clinic
Chanakha K. Navaratnarajah: Mayo Clinic
Marie Frenzke: Mayo Clinic
Xiao X. Wong: INRS and Institut Armand Frappier, University of Quebec, Laval, Quebec H7V 1B7, Canada
Bevan Sawatsky: INRS and Institut Armand Frappier, University of Quebec, Laval, Quebec H7V 1B7, Canada
Shyam Ramachandran: Department of Pediatrics University of Iowa Carver College of Medicine
Paul B. McCray: Department of Pediatrics University of Iowa Carver College of Medicine
Klaus Cichutek: Paul-Ehrlich-Institut, 63225 Langen, Germany
Veronika von Messling: INRS and Institut Armand Frappier, University of Quebec, Laval, Quebec H7V 1B7, Canada
Marc Lopez: INSERM, UMR891/CRCM and University of Aix-Marseille, 13009 Marseille, France
Roberto Cattaneo: Mayo Clinic

Nature, 2011, vol. 480, issue 7378, 530-533

Abstract: Nectin-4 is identified as a receptor for measles virus on epithelial cells, and measles virus might use nectin-4 for emergence in the airways.

Date: 2011
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DOI: 10.1038/nature10639

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