Response to self antigen imprints regulatory memory in tissues

Michael D. Rosenblum, Iris K. Gratz, Jonathan S. Paw, Karen Lee, Ann Marshak-Rothstein and Abul K. Abbas ()
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Michael D. Rosenblum: University of California San Francisco
Iris K. Gratz: University of California San Francisco
Jonathan S. Paw: University of California San Francisco
Karen Lee: Columbia University Medical Center
Ann Marshak-Rothstein: University of Massachusetts
Abul K. Abbas: University of California San Francisco

Nature, 2011, vol. 480, issue 7378, 538-542

Abstract: Thymus-derived regulatory T cells are activated by recognition of peripheral self antigen, persist in the target tissue on cessation of antigen exposure, and respond to re-exposure to self antigen with enhanced functional activity.

Date: 2011
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DOI: 10.1038/nature10664

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