Antibody-based protection against HIV infection by vectored immunoprophylaxis

Alejandro B. Balazs, Joyce Chen, Christin M. Hong, Dinesh S. Rao, Lili Yang and David Baltimore ()
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Alejandro B. Balazs: California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
Joyce Chen: California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
Christin M. Hong: California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
Dinesh S. Rao: David Geffen School of Medicine, University of California at Los Angeles, 10833 Le Conte Avenue, Los Angeles California 90095, USA
Lili Yang: California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
David Baltimore: California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA

Nature, 2012, vol. 481, issue 7379, 81-84

Abstract: A single injection of a viral vector that encodes antibodies able to neutralize most HIV strains protects humanized mice from HIV infection.

Date: 2012
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DOI: 10.1038/nature10660

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