Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel
Peng Yuan,
Manuel D. Leonetti,
Yichun Hsiung and
Roderick MacKinnon ()
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Peng Yuan: Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10065, USA
Manuel D. Leonetti: Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10065, USA
Yichun Hsiung: Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10065, USA
Roderick MacKinnon: Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10065, USA
Nature, 2012, vol. 481, issue 7379, 94-97
Abstract:
The crystal structure of the calcium-bound gating ring of a calcium- and voltage-activated potassium channel shows in detail how the effect of calcium binding on the gating ring produces the conformational change from closed to open.
Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:481:y:2012:i:7379:d:10.1038_nature10670
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DOI: 10.1038/nature10670
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