A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

Kim J. Png, Nils Halberg, Mitsukuni Yoshida and Sohail F. Tavazoie ()
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Kim J. Png: Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
Nils Halberg: Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
Mitsukuni Yoshida: Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
Sohail F. Tavazoie: Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue, New York, New York 10065, USA

Nature, 2012, vol. 481, issue 7380, 190-194

Abstract: The microRNA miR-126 suppresses the formation of breast cancer metastases via the suppression of several novel pro-angiogenic genes that cooperate in the recruitment of endothelial cells, leading to the formation of metastatic colonies.

Date: 2012
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DOI: 10.1038/nature10661

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