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Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2

Celia Andreu-Agullo (), Thomas Maurin, Craig B. Thompson and Eric C. Lai ()
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Celia Andreu-Agullo: Sloan-Kettering Institute, 1275 York Avenue, Box 252, New York, New York 10065, USA
Thomas Maurin: Sloan-Kettering Institute, 1275 York Avenue, Box 252, New York, New York 10065, USA
Craig B. Thompson: Sloan-Kettering Institute, 1275 York Avenue, Box 252, New York, New York 10065, USA
Eric C. Lai: Sloan-Kettering Institute, 1275 York Avenue, Box 252, New York, New York 10065, USA

Nature, 2012, vol. 481, issue 7380, 195-198

Abstract: Mammalian zinc finger protein Ars2 is revealed as a sequence-specific transcription factor that promotes the self-renewal of postnatal and adult neural stem cells by directly activating transcription of the pluripotency factor Sox2.

Date: 2012
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DOI: 10.1038/nature10712

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