Global landscape of HIV–human protein complexes

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Iván D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel and Nevan J. Krogan ()
Additional contact information
Stefanie Jäger: University of California
Peter Cimermancic: California Institute for Quantitative Biosciences, QB3
Natali Gulbahce: University of California
Jeffrey R. Johnson: University of California
Kathryn E. McGovern: University of California
Starlynn C. Clarke: University of California
Michael Shales: University of California
Gaelle Mercenne: University of Utah
Lars Pache: Sanford-Burnham Medical Research Institute
Kathy Li: University of California
Hilda Hernandez: University of California
Gwendolyn M. Jang: University of California
Shoshannah L. Roth: University of Pennsylvania
Eyal Akiva: California Institute for Quantitative Biosciences, QB3
John Marlett: The Salk Institute for Biological Studies
Melanie Stephens: University of Pennsylvania
Iván D’Orso: University of California
Jason Fernandes: University of California
Marie Fahey: University of California
Cathal Mahon: University of California
Anthony J. O’Donoghue: University of California
Aleksandar Todorovic: University of California
John H. Morris: University of California
David A. Maltby: University of California
Tom Alber: University of California
Gerard Cagney: Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
Frederic D. Bushman: University of Pennsylvania
John A. Young: The Salk Institute for Biological Studies
Sumit K. Chanda: Sanford-Burnham Medical Research Institute
Wesley I. Sundquist: University of Utah
Tanja Kortemme: California Institute for Quantitative Biosciences, QB3
Ryan D. Hernandez: California Institute for Quantitative Biosciences, QB3
Charles S. Craik: California Institute for Quantitative Biosciences, QB3
Alma Burlingame: California Institute for Quantitative Biosciences, QB3
Andrej Sali: California Institute for Quantitative Biosciences, QB3
Alan D. Frankel: California Institute for Quantitative Biosciences, QB3
Nevan J. Krogan: University of California

Nature, 2012, vol. 481, issue 7381, 365-370

Abstract: Affinity tagging, mass spectroscopy and a tailor-made scoring system are used to identify 497 high-confidence interactions between human proteins and human immunodeficiency virus proteins.

Date: 2012
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DOI: 10.1038/nature10719

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