Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy

Guangbo Chen, William D. Bradford, Chris W. Seidel and Rong Li ()
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Guangbo Chen: Stowers Institute for Medical Research, 1000 East 50th Street
William D. Bradford: Stowers Institute for Medical Research, 1000 East 50th Street
Chris W. Seidel: Stowers Institute for Medical Research, 1000 East 50th Street
Rong Li: Stowers Institute for Medical Research, 1000 East 50th Street

Nature, 2012, vol. 482, issue 7384, 246-250

Abstract: Aneuploidy is shown to be induced by pleiotropic stress conditions (especially Hsp90 inhbition) in yeast, leading to stress adaptation.

Date: 2012
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DOI: 10.1038/nature10795

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