Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK
Yu-yi Lin (),
Samara Kiihl,
Yasir Suhail,
Shang-Yun Liu,
Yi-hsuan Chou,
Zheng Kuang,
Jin-ying Lu,
Chin Ni Khor,
Chi-Long Lin,
Joel S. Bader,
Rafael Irizarry and
Jef D. Boeke ()
Additional contact information
Yu-yi Lin: Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Samara Kiihl: Johns Hopkins Bloomberg, School of Public Health
Yasir Suhail: Johns Hopkins University
Shang-Yun Liu: Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Yi-hsuan Chou: Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Zheng Kuang: The Johns Hopkins University School of Medicine
Jin-ying Lu: National Taiwan University Hospital, Taipei 100, Taiwan
Chin Ni Khor: National RNAi Core Facility, Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan
Chi-Long Lin: National RNAi Core Facility, Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan
Joel S. Bader: Johns Hopkins University
Rafael Irizarry: Johns Hopkins Bloomberg, School of Public Health
Jef D. Boeke: The Johns Hopkins University School of Medicine
Nature, 2012, vol. 482, issue 7384, 251-255
Abstract:
Genetic interaction profiles of human lysine deacetylases are generated by RNA interference knockdown to reveal the involvement of deacetylases in many critical biological processes, including metabolism, the cell cycle and development.
Date: 2012
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DOI: 10.1038/nature10804
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