Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search

Anthony L. Forget and Stephen C. Kowalczykowski ()
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Anthony L. Forget: University of California
Stephen C. Kowalczykowski: University of California

Nature, 2012, vol. 482, issue 7385, 423-427

Abstract: The search for DNA homology is vital to recombinational DNA repair and occurs by intersegment contact sampling wherein the three-dimensional conformational state of the double-stranded DNA target and the length of the homologous RecA–single-stranded DNA filament have important roles.

Date: 2012
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DOI: 10.1038/nature10782

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