Expression of tumour-specific antigens underlies cancer immunoediting

Michel DuPage, Claire Mazumdar, Leah M. Schmidt, Ann F. Cheung and Tyler Jacks ()
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Michel DuPage: Massachusetts Institute of Technology
Claire Mazumdar: Massachusetts Institute of Technology
Leah M. Schmidt: Massachusetts Institute of Technology
Ann F. Cheung: Massachusetts Institute of Technology
Tyler Jacks: Massachusetts Institute of Technology

Nature, 2012, vol. 482, issue 7385, 405-409

Abstract: This paper illustrates that immunosurveillance and immunoediting can occur in an oncogene-driven endogenous tumour model provided that the tumours carry strong neoantigens not present in the host.

Date: 2012
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DOI: 10.1038/nature10803

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