Outgrowth of single oncogene-expressing cells from suppressive epithelial environments

Cheuk T. Leung and Joan S. Brugge ()
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Cheuk T. Leung: Harvard Medical School
Joan S. Brugge: Harvard Medical School

Nature, 2012, vol. 482, issue 7385, 410-413

Abstract: The earliest stages of tumorigenesis are mimicked in a three-dimensional model of mammary epithelial cells, showing that oncogenes that can promote cell translocation can also drive clonal outgrowth.

Date: 2012
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DOI: 10.1038/nature10826

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