Opposite effects of fear conditioning and extinction on dendritic spine remodelling

Cora Sau Wan Lai, Thomas F. Franke and Wen-Biao Gan ()
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Cora Sau Wan Lai: Molecular Neurobiology Program, Skirball Institute, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA
Thomas F. Franke: New York University School of Medicine, 550 First Avenue, New York, New York 10016, USA
Wen-Biao Gan: Molecular Neurobiology Program, Skirball Institute, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA

Nature, 2012, vol. 483, issue 7387, 87-91

Abstract: In mouse frontal cortex, fear conditioning and extinction cause dendritic spine elimination and, respectively, formation to occur on the same dendritic branches in a cue- and location-specific manner.

Date: 2012
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DOI: 10.1038/nature10792

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