MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function

Thomas Metzger, Vincent Gache, Mu Xu, Bruno Cadot, Eric S. Folker, Brian E. Richardson, Edgar R. Gomes () and Mary K. Baylies ()
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Thomas Metzger: Program in Developmental Biology, Sloan-Kettering Institute
Vincent Gache: UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6
Mu Xu: Program in Developmental Biology, Sloan-Kettering Institute
Bruno Cadot: UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6
Eric S. Folker: Program in Developmental Biology, Sloan-Kettering Institute
Brian E. Richardson: Program in Developmental Biology, Sloan-Kettering Institute
Edgar R. Gomes: UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6
Mary K. Baylies: Program in Developmental Biology, Sloan-Kettering Institute

Nature, 2012, vol. 484, issue 7392, 120-124

Abstract: Skeletal muscle cells are multinucleate, and improper positioning of the nuclei contributes to muscle dysfunction.

Date: 2012
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DOI: 10.1038/nature10914

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