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Optogenetic stimulation of a hippocampal engram activates fear memory recall

Xu Liu, Steve Ramirez, Petti T. Pang, Corey B. Puryear, Arvind Govindarajan, Karl Deisseroth and Susumu Tonegawa ()
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Xu Liu: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Steve Ramirez: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Petti T. Pang: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Corey B. Puryear: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Arvind Govindarajan: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Karl Deisseroth: Stanford University
Susumu Tonegawa: RIKEN-MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Massachusetts Institute of Technology

Nature, 2012, vol. 484, issue 7394, 381-385

Abstract: The activation of a population of hippocampal neurons thought to encode a specific fear memory is shown to elicit freezing behaviour in mice.

Date: 2012
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Citations: View citations in EconPapers (18)

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DOI: 10.1038/nature11028

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