Stereospecific binding of a disordered peptide segment mediates BK channel inactivation

Vivian Gonzalez-Perez, Xu-Hui Zeng, Katie Henzler-Wildman and Christopher J. Lingle ()
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Vivian Gonzalez-Perez: Washington University School of Medicine
Xu-Hui Zeng: Washington University School of Medicine
Katie Henzler-Wildman: Washington University School of Medicine
Christopher J. Lingle: Washington University School of Medicine

Nature, 2012, vol. 485, issue 7396, 133-136

Abstract: Two-step BK channel inactivation mediated by an intrinsically disordered BK β-subunit peptide involves a stereospecific binding interaction that precedes blockade.

Date: 2012
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DOI: 10.1038/nature10994

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