Escaped DNA inflames the heart
Klitos Konstantinidis and
Richard N. Kitsis ()
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Klitos Konstantinidis: Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Richard N. Kitsis: Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Nature, 2012, vol. 485, issue 7397, 179-180
Abstract:
High blood pressure can damage heart muscle cells and their mitochondrial organelles. DNA from degraded mitochondria has been shown to trigger inflammation leading to heart failure. See Letter p.251
Date: 2012
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DOI: 10.1038/485179a
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