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Spatial partitioning of the regulatory landscape of the X-inactivation centre

Elphège P. Nora, Bryan R. Lajoie, Edda G. Schulz, Luca Giorgetti, Ikuhiro Okamoto, Nicolas Servant, Tristan Piolot, Nynke L. van Berkum, Johannes Meisig, John Sedat, Joost Gribnau, Emmanuel Barillot, Nils Blüthgen, Job Dekker () and Edith Heard ()
Additional contact information
Elphège P. Nora: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Bryan R. Lajoie: Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester
Edda G. Schulz: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Luca Giorgetti: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Ikuhiro Okamoto: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Nicolas Servant: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Tristan Piolot: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Nynke L. van Berkum: Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester
Johannes Meisig: Institute of Pathology, Charité–Universitätsmedizin, 10117 Berlin, and Institute of Theoretical Biology Humboldt Universität, 10115 Berlin, Germany
John Sedat: University of California San Francisco
Joost Gribnau: Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands
Emmanuel Barillot: Institut Curie, 26 rue d'Ulm, Paris F-75248, France
Nils Blüthgen: Institute of Pathology, Charité–Universitätsmedizin, 10117 Berlin, and Institute of Theoretical Biology Humboldt Universität, 10115 Berlin, Germany
Job Dekker: Programs in Systems Biology and Gene Function and Expression, University of Massachusetts Medical School, Worcester
Edith Heard: Institut Curie, 26 rue d'Ulm, Paris F-75248, France

Nature, 2012, vol. 485, issue 7398, 381-385

Abstract: High-order chromatin folding in topologically associating domains has a critical role in proper long-range transcriptional control around the Xist locus, and presumably throughout the genome.

Date: 2012
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DOI: 10.1038/nature11049

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