Genetic recombination is directed away from functional genomic elements in mice

Kevin Brick, Fatima Smagulova, Pavel Khil, R. Daniel Camerini-Otero () and Galina V. Petukhova ()
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Kevin Brick: National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
Fatima Smagulova: Uniformed Services University of Health Sciences
Pavel Khil: National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
R. Daniel Camerini-Otero: National Institute of Diabetes, Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892, USA
Galina V. Petukhova: Uniformed Services University of Health Sciences

Nature, 2012, vol. 485, issue 7400, 642-645

Abstract: Comparison of Prdm9−/− and wild-type mice reveals a role for the PRDM9 protein in directing the recombination machinery away from important genomic regions.

Date: 2012
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DOI: 10.1038/nature11089

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