Crystal structure of a voltage-gated sodium channel in two potentially inactivated states

Jian Payandeh, Tamer M. Gamal El-Din, Todd Scheuer, Ning Zheng () and William A. Catterall ()
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Jian Payandeh: University of Washington
Tamer M. Gamal El-Din: University of Washington
Todd Scheuer: University of Washington
Ning Zheng: University of Washington
William A. Catterall: University of Washington

Nature, 2012, vol. 486, issue 7401, 135-139

Abstract: X-ray crystal structures of a bacterial voltage-gated sodium channel in two ‘inactivated’ conformations are reported, revealing several conformational rearrangements that may underlie the electromechanical coupling of voltage sensor movement to inactivation of the pore.

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:486:y:2012:i:7401:d:10.1038_nature11077

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DOI: 10.1038/nature11077

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