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PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E. Shoelson, Christophe Benoist and Diane Mathis ()
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Daniela Cipolletta: Harvard Medical School
Markus Feuerer: Harvard Medical School
Amy Li: Harvard Medical School
Nozomu Kamei: Harvard Medical School
Jongsoon Lee: Harvard Medical School
Steven E. Shoelson: Harvard Medical School
Christophe Benoist: Harvard Medical School
Diane Mathis: Harvard Medical School

Nature, 2012, vol. 486, issue 7404, 549-553

Abstract: T regulatory (Treg) cells in visceral adipose tissue express high levels of the nuclear receptor peroxisome proliferator-activated receptor (PPAR)-γ, and fat-specific adaptation of Treg cells is dependent on PPAR-γ.

Date: 2012
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DOI: 10.1038/nature11132

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