A tumour suppressor network relying on the polyamine–hypusine axis

Claudio Scuoppo, Cornelius Miething, Lisa Lindqvist, José Reyes, Cristian Ruse, Iris Appelmann, Seungtai Yoon, Alexander Krasnitz, Julie Teruya-Feldstein, Darryl Pappin, Jerry Pelletier and Scott W. Lowe ()
Additional contact information
Claudio Scuoppo: Watson School of Biological Sciences
Cornelius Miething: Cold Spring Harbor Laboratory
Lisa Lindqvist: McGill University, Montreal, Quebec H3G 1Y6, Canada
José Reyes: Cold Spring Harbor Laboratory
Cristian Ruse: Cold Spring Harbor Laboratory
Iris Appelmann: Cold Spring Harbor Laboratory
Seungtai Yoon: Mount Sinai School of Medicine
Alexander Krasnitz: Cold Spring Harbor Laboratory
Julie Teruya-Feldstein: Memorial Sloan-Kettering Cancer Center
Darryl Pappin: Cold Spring Harbor Laboratory
Jerry Pelletier: McGill University, Montreal, Quebec H3G 1Y6, Canada
Scott W. Lowe: Watson School of Biological Sciences

Nature, 2012, vol. 487, issue 7406, 244-248

Abstract: AMD1 and eIF5A are identified as two genes involved in the polyamine–hypusine pathway, a new tumour suppressor network regulating apoptosis.

Date: 2012
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DOI: 10.1038/nature11126

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