Greasy tags for protein removal

Taavi K. Neklesa and Craig M. Crews ()
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Taavi K. Neklesa: Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520, USA.
Craig M. Crews: Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520, USA.

Nature, 2012, vol. 487, issue 7407, 308-309

Abstract: Most proteins in the human body are difficult targets for small-molecule drugs. This problem may have been overcome with the discovery of molecules that induce protein degradation, suggesting fresh, modular approaches to drug discovery.

Date: 2012
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DOI: 10.1038/487308a

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