Heterogeneous pathways and timing of factor departure during translation initiation

Albert Tsai, Alexey Petrov, R. Andrew Marshall, Jonas Korlach, Sotaro Uemura () and Joseph D. Puglisi ()
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Albert Tsai: Stanford University School of Medicine
Alexey Petrov: Stanford University School of Medicine
R. Andrew Marshall: Stanford University School of Medicine
Jonas Korlach: Pacific Biosciences, 1380 Willow Rd
Sotaro Uemura: Stanford University School of Medicine
Joseph D. Puglisi: Stanford University School of Medicine

Nature, 2012, vol. 487, issue 7407, 390-393

Abstract: A single-molecule approach is used to investigate the kinetics of assembly of the translation initiation complex, revealing that there is more than one pathway by which the necessary factors can assemble.

Date: 2012
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DOI: 10.1038/nature11172

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