Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

Panteleimon Rompolas, Elizabeth R. Deschene, Giovanni Zito, David G. Gonzalez, Ichiko Saotome, Ann M. Haberman and Valentina Greco ()
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Panteleimon Rompolas: Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine
Elizabeth R. Deschene: Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine
Giovanni Zito: Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine
David G. Gonzalez: Yale School of Medicine
Ichiko Saotome: Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine
Ann M. Haberman: Yale School of Medicine
Valentina Greco: Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine

Nature, 2012, vol. 487, issue 7408, 496-499

Abstract: A non-invasive method is used to study and manipulate hair-follicle regeneration over time in live mice, and shows that hair growth involves spatially regulated cell divisions, cellular reorganization and migration of epithelial cells, and that the mesenchyme is required for hair growth.

Date: 2012
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DOI: 10.1038/nature11218

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