Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

Julie A. Mattison (), George S. Roth, T. Mark Beasley, Edward M. Tilmont, April M. Handy, Richard L. Herbert, Dan L. Longo, David B. Allison, Jennifer E. Young, Mark Bryant, Dennis Barnard, Walter F. Ward, Wenbo Qi, Donald K. Ingram () and Rafael de Cabo ()
Additional contact information
Julie A. Mattison: Laboratory of Experimental Gerontology, National Institute on Aging, NIH Animal Center, 16701 Elmer School Road Building 103
George S. Roth: GeroScience
T. Mark Beasley: Ryals Public Health Bldg 343C University of Alabama at Birmingham, 1530 3rd Avenue S, Birmingham, Alabama 35294, USA
Edward M. Tilmont: Laboratory of Experimental Gerontology, National Institute on Aging, NIH Animal Center, 16701 Elmer School Road Building 103
April M. Handy: Laboratory of Experimental Gerontology, National Institute on Aging, NIH Animal Center, 16701 Elmer School Road Building 103
Richard L. Herbert: National Institute of Allergy and Infectious Disease, NIH Animal Center, 16701 Elmer School Road, Building 102, Dickerson, Maryland 20842, USA
Dan L. Longo: Laboratory of Molecular Biology and Immunology, National Institute on Aging, NIH, 251 Bayview Boulevard Room 08C228, Baltimore, Maryland 21224, USA
David B. Allison: Office of Energetics, University of Alabama at Birmingham, 1665 University Boulevard
Jennifer E. Young: Laboratory of Experimental Gerontology, National Institute on Aging, NIH Animal Center, 16701 Elmer School Road Building 103
Mark Bryant: Office of the Director, Diagnostic and Research Services Branch, NIH, Bldg 28A, Room 114, 28 Service Road West, Bethesda, Maryland 20814, USA
Dennis Barnard: Office of the Director, Diagnostic and Research Services Branch, NIH, Building 14A, Room 119A, 14 Service Road West, Bethesda, Maryland 20814, USA
Walter F. Ward: University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, USA
Wenbo Qi: University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, USA
Donald K. Ingram: Nutritional Neuroscience and Aging Laboratory, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA
Rafael de Cabo: Laboratory of Experimental Gerontology, National Institute on Aging, NIH, 251 Bayview Boulevard Suite 100, Baltimore, Maryland 21224, USA

Nature, 2012, vol. 489, issue 7415, 318-321

Abstract: The results of a 23-year study of caloric restriction in rhesus macaques are reported; restricted caloric intake did not increase survival, but improved the metabolic profile of monkeys started at older ages and showed a trend towards delaying age-associated disease in monkeys started at a young age.

Date: 2012
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature11432 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:489:y:2012:i:7415:d:10.1038_nature11432

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature11432

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().