When more is less

Lei Jiang () and Ralph J. DeBerardinis
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Lei Jiang: Lei Jiang and Ralph J. DeBerardinis are at the Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8502, USA.
Ralph J. DeBerardinis: Lei Jiang and Ralph J. DeBerardinis are at the Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8502, USA.

Nature, 2012, vol. 489, issue 7417, 511-512

Abstract: A tightly regulated enzyme balances energy production and the synthesis of macromolecules from glucose in cancer cells. Upsetting this balance by stimulating the enzyme's activity can suppress tumour growth in mice.

Date: 2012
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DOI: 10.1038/489511a

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