Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
Ayumi Yoshizaki,
Tomomitsu Miyagaki,
David J. DiLillo,
Takashi Matsushita,
Mayuka Horikawa,
Evgueni I. Kountikov,
Rosanne Spolski,
Jonathan C. Poe,
Warren J. Leonard and
Thomas F. Tedder ()
Additional contact information
Ayumi Yoshizaki: Duke University Medical Center
Tomomitsu Miyagaki: Duke University Medical Center
David J. DiLillo: Duke University Medical Center
Takashi Matsushita: Duke University Medical Center
Mayuka Horikawa: Duke University Medical Center
Evgueni I. Kountikov: Duke University Medical Center
Rosanne Spolski: Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health
Jonathan C. Poe: Duke University Medical Center
Warren J. Leonard: Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health
Thomas F. Tedder: Duke University Medical Center
Nature, 2012, vol. 491, issue 7423, 264-268
Abstract:
IL-21- and CD40-dependent cognate interactions with T cells are identified as key drivers for the generation of IL-10-producing regulatory B cells, which can protect against autoimmune disease.
Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:491:y:2012:i:7423:d:10.1038_nature11501
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DOI: 10.1038/nature11501
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