Genetic programs constructed from layered logic gates in single cells

Tae Seok Moon, Chunbo Lou, Alvin Tamsir, Brynne C. Stanton and Christopher A. Voigt ()
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Tae Seok Moon: Synthetic Biology Center, Massachusetts Institute of Technology
Chunbo Lou: Synthetic Biology Center, Massachusetts Institute of Technology
Alvin Tamsir: Tetrad Graduate Program, University of California San Francisco
Brynne C. Stanton: Synthetic Biology Center, Massachusetts Institute of Technology
Christopher A. Voigt: Synthetic Biology Center, Massachusetts Institute of Technology

Nature, 2012, vol. 491, issue 7423, 249-253

Abstract: The creation of orthogonal ‘AND’ logic gates by combining DNA-binding proteins into complex, layered circuits opens the way to the design of programmable integrated circuits in synthetic biology.

Date: 2012
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DOI: 10.1038/nature11516

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