Aberrant light directly impairs mood and learning through melanopsin-expressing neurons

Tara A. LeGates, Cara M. Altimus, Hui Wang, Hey-Kyoung Lee, Sunggu Yang, Haiqing Zhao, Alfredo Kirkwood, E. Todd Weber and Samer Hattar ()
Additional contact information
Tara A. LeGates: Johns Hopkins University
Cara M. Altimus: Johns Hopkins University
Hui Wang: Johns Hopkins University
Hey-Kyoung Lee: Johns Hopkins University
Sunggu Yang: Johns Hopkins University
Haiqing Zhao: Johns Hopkins University
Alfredo Kirkwood: Johns Hopkins University
E. Todd Weber: Rider University
Samer Hattar: Johns Hopkins University

Nature, 2012, vol. 491, issue 7425, 594-598

Abstract: Mice subjected to an aberrant daily light cycle that still maintain the circadian timing system are shown to exhibit increased depression-like behaviours and disruptions in synaptic plasticity and cognitive function.

Date: 2012
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DOI: 10.1038/nature11673

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