Identification of a rudimentary neural crest in a non-vertebrate chordate

Philip Barron Abitua, Eileen Wagner, Ignacio A. Navarrete and Michael Levine ()
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Philip Barron Abitua: Center for Integrative Genomics, Genomics and Development, University of California
Eileen Wagner: Center for Integrative Genomics, Genomics and Development, University of California
Ignacio A. Navarrete: Center for Integrative Genomics, Genomics and Development, University of California
Michael Levine: Center for Integrative Genomics, Genomics and Development, University of California

Nature, 2012, vol. 492, issue 7427, 104-107

Abstract: The sessile tunicate Ciona intestinalis possesses a lineage of cells, originating at the margin of the neural plate, that express several neural crest specification genes and can be reprogrammed into migrating ectomesenchyme by the targeted misexpression of Twist.

Date: 2012
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DOI: 10.1038/nature11589

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