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Fucose sensing regulates bacterial intestinal colonization

Alline R. Pacheco, Meredith M. Curtis, Jennifer M. Ritchie, Diana Munera, Matthew K. Waldor, Cristiano G. Moreira and Vanessa Sperandio ()
Additional contact information
Alline R. Pacheco: University of Texas Southwestern Medical Center
Meredith M. Curtis: University of Texas Southwestern Medical Center
Jennifer M. Ritchie: Brigham and Women’s Hospital, Harvard Medical School
Diana Munera: Brigham and Women’s Hospital, Harvard Medical School
Matthew K. Waldor: Brigham and Women’s Hospital, Harvard Medical School
Cristiano G. Moreira: University of Texas Southwestern Medical Center
Vanessa Sperandio: University of Texas Southwestern Medical Center

Nature, 2012, vol. 492, issue 7427, 113-117

Abstract: FusKR, a fucose-sensing two-component system, has been identified in enterohaemorrhagic E. coli, linking fucose utilization and virulence factor gene expression and providing insight into how sensing of a host signal can facilitate bacterial colonization.

Date: 2012
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DOI: 10.1038/nature11623

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