Molecular hurdles cleared with ease

Michael A. Trakselis () and Brian W. Graham
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Michael A. Trakselis: University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Brian W. Graham: University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

Nature, 2012, vol. 492, issue 7428, 195-197

Abstract: Single-molecule studies reveal that a ring-like enzyme that encircles and 'slides' along one strand of duplex DNA, separating it from the other strand, overcomes molecular barriers in its path by transiently opening its ring. See Article p.205

Date: 2012
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DOI: 10.1038/nature11758

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